Institutional-Grade Biospecimens. Exclusively for Down Syndrome Research.

The DSA Biobank provides researchers with immediate access to high-quality biospecimens — collected from individuals with Down syndrome and their immediate family members, processed at Cincinnati Children’s Hospital Medical Center, and available without the delays of independent recruitment. Our inventory of 5,000+ aliquots of serum, plasma, and DNA is ready to support your next study.

Who benefits from the use of DSA Biobank samples?

Investigators and clinicians gain immediate access to well-annotated cohorts — eliminating the recruitment delays that typically add 12–18 months to study timelines. DSA Biobank samples have already supported NIH-funded research and peer-reviewed publications.

What’s Available Right Now

DSA Biobank currently holds more than 5,000 aliquots of broadly consented biospecimens — available for a wide range of future studies without re-consenting. Our collection includes:

5,000+ aliquots of serum, plasma, and DNA

Consented participants, including pediatric and adult representation

67 mother-child dyads and 16 full family triads

Broadly consented samples — no re-consenting required for new studies

IRB-approved collection protocols

Institutional processing and storage at Cincinnati Children’s Hospital Medical Center

What types of samples are stored in a biobank?

DSA Biobank’s current inventory is composed of blood-derived biospecimens: serum, plasma, and DNA. These sample types support basic, translational, and clinical research across the health conditions most prevalent in Down syndrome — including Alzheimer’s disease, leukemia and blood disorders, congenital heart defects, autoimmune disease, keratoconus and ocular conditions, and thyroid and metabolic disorders, among others.

Additional biospecimen types may be available through custom cohort recruitment. Contact us to discuss your specific study requirements.

Why is biobanking important for Down syndrome?

DSA Biobank gives investigators a meaningful head start — with 5,000+ aliquots available now and a typical turnaround of 4–6 weeks from request to shipment. No independent recruitment. No 18-month delays.

Ready to see what’s available for your study?

Have additional questions?
Visit our Researcher FAQ page or contact us to discuss your study.

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