The DSA Biobank primarily provides blood-derived biospecimens, including serum, plasma, and DNA. Additional biospecimens (e.g., RNA, PBMCs, saliva) may be available or supported through custom cohort development based on study needs. Our team works with researchers to align available inventory or develop cohorts to meet specific study requirements.

All biospecimens are processed and stored at Cincinnati Children’s Hospital Medical Center — consistently ranked among the top children’s hospitals in the U.S. and a leading recipient of NIH pediatric research grants. CCHMC’s institutional biobanking team ensures samples meet the quality standards required for publication and regulatory submission.

Individuals with Down syndrome, along with their parents or siblings, are eligible to participate. This supports the development of structured family cohorts (e.g., dyads and triads).

Biospecimens are collected through clinical collection sites and coordinated home phlebotomy when appropriate, enabling both in-person and remote participation.

DSA Biobank includes both pediatric and adult participants. Collection methods vary based on age and logistics, including on-site and home collection options.

Yes. Participants complete health profiles that can be linked to biospecimens, providing additional context for research use.

Participants are assigned unique identifiers, and all biospecimens and data are de-identified prior to release. No personally identifying information is shared with researchers.

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Participants provide broad consent for future research use of biospecimens, with assent obtained when applicable.

All biospecimen collection and use adhere to established ethical standards, including informed consent, privacy protections, and institutional oversight.

Yes. We work with researchers to align available samples or support prospective recruitment based on defined inclusion criteria.

DSA Biobank operates on a cost-recovery model, keeping pricing accessible for academic and investigator-initiated research. Base pricing starts at $200 per aliquot for serum and plasma, and $250 per aliquot for DNA. Final pricing depends on sample type, volume, and cohort configuration. Submit a Researcher Request Form for a full feasibility assessment and project-specific pricing.

Start by submitting a Researcher Request Form — it takes about five minutes and asks only for a brief study summary. Our team responds with a feasibility assessment typically within one week. If samples are available, we move to Scientific Review, then  Material License and Transfer Agreement (MTA) and can ship within 4–6 weeks of execution.